Use of high-resolution pulse oximetry to timely detect clinical deterioration during sepsis

Recently, the sepsis research group in Groningen has been engaged in a study to test whether signs of clinical deterioration in patients with (severe) infection could be detected more quickly by means of a "wearable. The idea is based on the current ongoing research led by Jan ter Maaten, titled "SepsiVit." In this research, vital parameters are measured continuously. By analyzing the course of vital parameters, rather than looking at point measurements, a deteriorating clinical condition can be detected earlier (Quinten, Scand J Trauma Resusc Emerg Med, 2018).

However, a disadvantage of continuous measurement of vital signs is that it limits patient mobility by being connected to a bed-side monitor 24 hours a day. The current study is testing whether the "OSAsense S18," a watch developed for ambulatory diagnosis of sleep apnea by high-resolution (50Hz) continuous pulse oximetry in the first-line, could take over this function from the monitor.

In collaboration with the Department of Technical Medicine at the University of Twente, the raw data obtained through the watch will be analyzed with the aim of developing an algorithm capable of early detection of a deteriorating clinical condition. The research team, which further consists of Tycho Olgers, Jack Ligtenberg, Vincent Quinten and Hjalmar Bouma in collaboration with DiagnOSAS B.V., aims to develop a wearable device for early detection of clinical deterioration in patients with (severe) infection. Findings from this study may also be relevant for clinical patients without infections, or for patients discharged home, with or without hospital care, where additional monitoring is desired.

https://www.acuteinternisten.nl/osasense-continu-monitoring/